Tumor hypoxia and hypoxic adaptation of cancer cells represent major barriers to successful cancer treatment.We revealed that improved antioxidant capacity contributes to increased radioresistance of cancer cells with tolerance to chronic-cycling severe hypoxia/reoxygenation stress.We hypothesized, that the improved tolerance to oxidative stress wi
Computational strain design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models.In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations used during parameterization.In this effort, we appl
ABSTRACT Mandacaru (Cereus jamacaru DC - Cactaceae) possesses peculiar physiological and morphological characteristics that allow it to withstand long periods of scarcity and to adapt to different environments.Several uses have also been reported Baby One-Pieces for the species from the 17th century to the present day.Given this history and the imp
The mangrove ecosystem is one of the most productive ecosystems Testosterone on the planet with relevant ecological importance.It offers several services such as protection of the coastal region, immobilization of contaminants, as it is a food source and refuge for various organisms.However, mangroves are threatened by human activities.Oil spills i
ZINC CHELATE 25 MG Summary: The catalytic activity of most epigenetic enzymes requires a metabolite produced by central carbon metabolism as a cofactor or (co-)substrate.The concentrations of these metabolites undergo dynamic changes in response to nutrient levels and environmental conditions, reprogramming metabolic processes and epigenetic landsc